On the Clark-Jacob Version of SPLICE/AS

A Survey of Authentication Protocol Literature: Version 1.0

Creutzfeldt-Jacob Disease in an Iranian Patient Confirmed By Brain Autopsy

Creutzfeldt-Jacob disease is the most common form of prion diseases, which have become public health problems in the last two decades because of the high number of reported cases of mad cow disease in Great Britain and other countries. Creutzfeldt-Jacob disease is a fatal situation with known cardinal clinical features including progressive memory loss and myoclonic seizure disorder. In this re...

تأثیر آدنوزین ´5تری فسفات در القای آپوپتوز و مهار بیان ژن Survivin و واریانت پیرایشی ضد آپوپتوزی SUR-3B آن در سلول های K562

Introduction: Leukemia is a heterogeneous malignant disease in which progression at the level of CD34+ cells has a major impact in drug resistance and relapse. The multi-drug resistance gene product, P-glycoprotein is an inhibitor of apoptosis proteins (IAPs), such as Survivin that are expressed simultaneously with several putative drug resistance parameters in CD34+ leukemia cells. In fact, IA...

Identification of a Novel Splice Site Mutation in RUNX2 Gene in a Family with Rare Autosomal Dominant Cleidocranial Dysplasia

Introduction: Pathogenic variants of RUNX2, a gene that encodes an osteoblast-specific transcription factor, have been shown as the cause of CCD, which is a rare hereditary skeletal and dental disorder with dominant mode of inheritance and a broad range of clinical variability. Due to the relative lack of clinical complications resulting in CCD, the medical diagnosis of this disorder is challen...

Fragility Curves for Reinforced Concrete Frames with Lap-Spliced Columns

Placing column lap-splice in the locations of possible nonlinear deformation may adversely affect the structures response to strong ground motions. Localization of damage in splice zone may change the structural response and prevent the load redistribution and development of a uniform pattern of nonlinear excursions among the various members. Validated by existing laboratory experiments, this s...